8P08
Crystal structure of human CLK1 in complex with Leucettinib-21
Summary for 8P08
Entry DOI | 10.2210/pdb8p08/pdb |
Descriptor | Dual specificity protein kinase CLK1, (4~{Z})-4-(1,3-benzothiazol-6-ylmethylidene)-2-[[(2~{R})-1-methoxy-4-methyl-pentan-2-yl]amino]-1~{H}-imidazol-5-one (3 entities in total) |
Functional Keywords | kinase, typ1 inhibitor, clk1, structural genomics, structural genomics consortium, sgc, transferase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 39939.97 |
Authors | Kraemer, A.,Schroeder, M.,Meijer, L.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2023-05-09, release date: 2023-05-17, Last modification date: 2024-06-19) |
Primary citation | Kraemer, A.,Schroeder, M.,Meijer, L.,Knapp, S.,Structural Genomics Consortium (SGC) Crystal structure of human CLK1 bound in complex with Leucettinib-21 To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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