8ONH
Variant Surface Glycoprotein VSG11wt-Oil
Summary for 8ONH
Entry DOI | 10.2210/pdb8onh/pdb |
Descriptor | Variant surface glycoprotein, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (10 entities in total) |
Functional Keywords | variant surface glycoprotein suramin trypanosomiasis drug resistance glycosylation, membrane protein |
Biological source | Trypanosoma brucei brucei |
Total number of polymer chains | 18 |
Total formula weight | 809348.63 |
Authors | Zeelen, J.P.,Stebbins, C.E.,Foti, K.,Gkeka, A.,Vlachou, E.P. (deposition date: 2023-04-03, release date: 2023-09-13) |
Primary citation | Dakovic, S.,Zeelen, J.P.,Gkeka, A.,Chandra, M.,van Straaten, M.,Foti, K.,Zhong, J.,Vlachou, E.P.,Aresta-Branco, F.,Verdi, J.P.,Papavasiliou, F.N.,Stebbins, C.E. A structural classification of the variant surface glycoproteins of the African trypanosomey. Plos Negl Trop Dis, 17:e0011621-e0011621, 2023 Cited by PubMed: 37656766DOI: 10.1371/journal.pntd.0011621 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.59 Å) |
Structure validation
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