8JV5
Cryo-EM structure of the zebrafish P2X4 receptor in complex with BX430
Summary for 8JV5
Entry DOI | 10.2210/pdb8jv5/pdb |
EMDB information | 36668 |
Descriptor | P2X purinoceptor, 1-[2,6-bis(bromanyl)-4-propan-2-yl-phenyl]-3-pyridin-3-yl-urea, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total) |
Functional Keywords | atp, allosteric modulator, channel, transport protein |
Biological source | Danio rerio (zebrafish) |
Total number of polymer chains | 3 |
Total formula weight | 121661.16 |
Authors | Hattori, M.,Shen, C. (deposition date: 2023-06-27, release date: 2023-10-18, Last modification date: 2023-10-25) |
Primary citation | Shen, C.,Zhang, Y.,Cui, W.,Zhao, Y.,Sheng, D.,Teng, X.,Shao, M.,Ichikawa, M.,Wang, J.,Hattori, M. Structural insights into the allosteric inhibition of P2X4 receptors. Nat Commun, 14:6437-6437, 2023 Cited by PubMed: 37833294DOI: 10.1038/s41467-023-42164-y PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.23 Å) |
Structure validation
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