8J1K

co-crystal structure of non-carboxylic acid inhibitor with PHD2

Summary for 8J1K

• Entry DOI: 10.2210/pdb8j1k/pdb
• Descriptor: Egl nine homolog 1, N-[(6-cyanopyridin-3-yl)methyl]-5-oxidanyl-2-[(3R)-3-oxidanylpyrrolidin-1-yl]-1,7-naphthyridine-6-carboxamide, MANGANESE (II) ION, ... (4 entities in total)
• Functional Keywords: oxidoreductase-inhibitor complex, oxidoreductase/inhibitor
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 24944.22

Authors

Xu, J.,Fu, Y.,Ding, X.,Meng, Q.,Wang, L.,Zhang, M.,Ding, X.,Ren, F.,Zhavoronkov, A. (deposition date: 2023-04-13, release date: 2024-04-17)

• Primary citation: Xu, J.,Fu, Y.,Ding, X.,Meng, Q.,Wang, L.,Man, Z.,Ding, X.,Ren, F.,Zhavoronkov, A.; co-crystal structure of non-carboxylic acid inhibitor with PHD2; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.451 Å)