8J1K
co-crystal structure of non-carboxylic acid inhibitor with PHD2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Egl nine homolog 1 | polymer | 218 | 24498.9 | 1 | UniProt (Q9GZT9) Pfam (PF13640) In PDB | Homo sapiens (human) | Hypoxia-inducible factor prolyl hydroxylase 2,HIF-PH2,HIF-prolyl hydroxylase 2,HPH-2,Prolyl hydroxylase domain-containing protein 2,PHD2,SM-20 |
| 2 | A | N-[(6-cyanopyridin-3-yl)methyl]-5-oxidanyl-2-[(3R)-3-oxidanylpyrrolidin-1-yl]-1,7-naphthyridine-6-carboxamide | non-polymer | 390.4 | 1 | Chemie (SY6) | |||
| 3 | A | MANGANESE (II) ION | non-polymer | 54.9 | 1 | Chemie (MN) | |||
| 4 | water | water | 18.0 | 30 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 24498.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 445.3 | |
| All* | Total formula weight | 24944.2 |
