8HY7
EGFR kinase domain mutant "TMLR" with compound 28f
Summary for 8HY7
Entry DOI | 10.2210/pdb8hy7/pdb |
Descriptor | Epidermal growth factor receptor, ~{N}-[3-[[6-fluoranyl-2-[[4-(4-methylpiperazin-1-yl)phenyl]amino]quinazolin-4-yl]amino]phenyl]prop-2-enamide (3 entities in total) |
Functional Keywords | inhibitor, complex, egfr, structural protein |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 37989.91 |
Authors | |
Primary citation | Wang, Y.X.,Wu, C.Y. The crystal structure of EGFR kinase domain(T790M/L858R) in complex with compound 28f To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.91 Å) |
Structure validation
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