8G1A
Cryo-EM structure of Nav1.7 with CBD
Summary for 8G1A
Entry DOI | 10.2210/pdb8g1a/pdb |
EMDB information | 29665 |
Descriptor | Sodium channel protein type 9 subunit alpha, 1-O-OCTADECYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ... (11 entities in total) |
Functional Keywords | cryo-em, sodium channel, vgsc, nav1.7, cbd, membrane protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 3 |
Total formula weight | 292863.27 |
Authors | |
Primary citation | Huang, J.,Fan, X.,Jin, X.,Jo, S.,Zhang, H.B.,Fujita, A.,Bean, B.P.,Yan, N. Cannabidiol inhibits Na v channels through two distinct binding sites. Nat Commun, 14:3613-3613, 2023 Cited by PubMed: 37330538DOI: 10.1038/s41467-023-39307-6 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.8 Å) |
Structure validation
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