8FW6
Human Lactate Dehydrogenase A in Complex with Inhibitor CHK-336
Summary for 8FW6
Entry DOI | 10.2210/pdb8fw6/pdb |
Descriptor | L-lactate dehydrogenase A chain, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, (2P)-2-{5-(cyclopropylmethyl)-3-(4-fluorophenyl)-4-[(3-fluoro-4-sulfamoylphenyl)methyl]-1H-pyrazol-1-yl}-1,3-thiazole-4-carboxylic acid, ... (6 entities in total) |
Functional Keywords | ldha hldha human lactate dehydrogenase a, oxidoreductase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 78680.38 |
Authors | |
Primary citation | Lowther, W.T.,Gumpena, R. Human Lactate Dehydrogenase A in complex with inhibitor CHK-336 To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.34 Å) |
Structure validation
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