8F86
SIRT6 bound to an H3K9Ac nucleosome
Summary for 8F86
Entry DOI | 10.2210/pdb8f86/pdb |
EMDB information | 28915 |
Descriptor | Histone H3.2, Histone H4, Histone H2A type 1, ... (9 entities in total) |
Functional Keywords | nucleosome, sirtuin6, histone deacylation, h3k9ac, gene regulation |
Biological source | Xenopus laevis (African clawed frog) More |
Total number of polymer chains | 11 |
Total formula weight | 262113.59 |
Authors | Markert, J.,Whedon, S.,Wang, Z.,Cole, P.,Farnung, L. (deposition date: 2022-11-21, release date: 2023-04-05, Last modification date: 2024-03-13) |
Primary citation | Wang, Z.A.,Markert, J.W.,Whedon, S.D.,Yapa Abeywardana, M.,Lee, K.,Jiang, H.,Suarez, C.,Lin, H.,Farnung, L.,Cole, P.A. Structural Basis of Sirtuin 6-Catalyzed Nucleosome Deacetylation. J.Am.Chem.Soc., 145:6811-6822, 2023 Cited by PubMed: 36930461DOI: 10.1021/jacs.2c13512 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.1 Å) |
Structure validation
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