8DIV
Crystal structure of NavAb I22V as a basis for the human Nav1.7 Inherited Erythromelalgia I136V mutation
Summary for 8DIV
Entry DOI | 10.2210/pdb8div/pdb |
Descriptor | Ion transport protein, beta-D-glucopyranose, 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ... (5 entities in total) |
Functional Keywords | voltage-gated sodium channel ion transport protein, membrane protein |
Biological source | Aliarcobacter butzleri RM4018 |
Total number of polymer chains | 1 |
Total formula weight | 34579.88 |
Authors | Wisedchaisri, G.,Gamal El-Din, T.M.,Powell, N.M.,Zheng, N.,Catterall, W.A. (deposition date: 2022-06-29, release date: 2023-10-25, Last modification date: 2023-11-15) |
Primary citation | Wisedchaisri, G.,Gamal El-Din, T.M.,Powell, N.M.,Zheng, N.,Catterall, W.A. Structural basis for severe pain caused by mutations in the voltage sensors of sodium channel NaV1.7. J.Gen.Physiol., 155:-, 2023 Cited by PubMed: 37903281DOI: 10.1085/jgp.202313450 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.54 Å) |
Structure validation
Download full validation report