8DCC

SARS-CoV-2 Receptor-Binding Domain SPEEDesign Immunogen 3 Bound to P2B-2F6 Fab

Summary for 8DCC

Entry DOI	10.2210/pdb8dcc/pdb
Descriptor	Spike protein S1, P2B-2F6 Fab light chain, P2B-2F6 Fab heavy chain, ... (5 entities in total)
Functional Keywords	immunogen, antigen, design, vaccine, viral protein-immune system complex, viral protein/immune system
Biological source	Severe acute respiratory syndrome coronavirus 2 More
Total number of polymer chains	3
Total formula weight	72193.37
Authors	Dickey, T.D.,Tolia, N.H. (deposition date: 2022-06-16, release date: 2022-07-06, Last modification date: 2023-10-18)
Primary citation	Dickey, T.H.,Tang, W.K.,Butler, B.,Ouahes, T.,Orr-Gonzalez, S.,Salinas, N.D.,Lambert, L.E.,Tolia, N.H. Design of the SARS-CoV-2 RBD vaccine antigen improves neutralizing antibody response. Sci Adv, 8:eabq8276-eabq8276, 2022 Cited by PubMed: 36103542 DOI: 10.1126/sciadv.abq8276 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.6 Å)

Structure validation