8D7H
Cryo-EM structure of human CLCF1 in complex with CRLF1 and CNTFR alpha
Summary for 8D7H
Entry DOI | 10.2210/pdb8d7h/pdb |
EMDB information | 27230 |
Descriptor | Ciliary neurotrophic factor receptor subunit alpha, Cardiotrophin-like cytokine factor 1, Cytokine receptor-like factor 1, ... (5 entities in total) |
Functional Keywords | cytokine signaling, clcf1, cntfr alpha, crlf1, cytokine |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 6 |
Total formula weight | 219466.12 |
Authors | |
Primary citation | Zhou, Y.,Stevis, P.E.,Cao, J.,Saotome, K.,Wu, J.,Glatman Zaretsky, A.,Haxhinasto, S.,Yancopoulos, G.D.,Murphy, A.J.,Sleeman, M.W.,Olson, W.C.,Franklin, M.C. Structural insights into the assembly of gp130 family cytokine signaling complexes. Sci Adv, 9:eade4395-eade4395, 2023 Cited by PubMed: 36930708DOI: 10.1126/sciadv.ade4395 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.4 Å) |
Structure validation
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