8D3A
Crystal Structure of DH475 Fab in complex with Man9
Summary for 8D3A
Entry DOI | 10.2210/pdb8d3a/pdb |
Descriptor | DH475 Fab heavy chain, DH475 Fab light chain, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total) |
Functional Keywords | fab fragment, hiv-1, antibody, immune system, immune system-antigen complex, immune system/antigen |
Biological source | Homo sapiens More |
Total number of polymer chains | 2 |
Total formula weight | 49497.60 |
Authors | Finkelstein, M.,Fera, D. (deposition date: 2022-06-01, release date: 2022-10-12, Last modification date: 2024-10-16) |
Primary citation | Finkelstein, M.T.,Parker Miller, E.,Erdman, M.C.,Fera, D. Analysis of two cooperating antibodies unveils immune pressure imposed on HIV Env to elicit a V3-glycan supersite broadly neutralizing antibody lineage. Front Immunol, 13:962939-962939, 2022 Cited by PubMed: 36225920DOI: 10.3389/fimmu.2022.962939 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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