8CR8

human Interleukin-23

Summary for 8CR8

• Entry DOI: 10.2210/pdb8cr8/pdb
• Related: 8C7M 8CR5 8CR6
• Descriptor: Interleukin-12 subunit beta, Interleukin-23 subunit alpha, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• Functional Keywords: heterodimer, cytokine, extracellular, inflammation, fibronectin type iii
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 59590.77

Authors

Bloch, Y.,Savvides, S.N. (deposition date: 2023-03-08, release date: 2024-02-07, Last modification date: 2024-05-01)

• Primary citation: Bloch, Y.,Felix, J.,Merceron, R.,Provost, M.,Symakani, R.A.,De Backer, R.,Lambert, E.,Mehdipour, A.R.,Savvides, S.N.; Structures of complete extracellular receptor assemblies mediated by IL-12 and IL-23.; Nat.Struct.Mol.Biol., 31:591-597, 2024; PubMed: 38287195; DOI: 10.1038/s41594-023-01190-6

Experimental method

X-RAY DIFFRACTION (2 Å)