8BEC

Crystal structure of the SARS-CoV-2 S RBD in complex with pT1375 scFV

Summary for 8BEC

• Entry DOI: 10.2210/pdb8bec/pdb
• Descriptor: pT1375 single-chain Fv, Spike protein S1, alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
• Functional Keywords: protein binding/immune system, protein binding
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 99413.96

Authors

Hansen, G.,Ssebyatika, G.L.,Krey, T. (deposition date: 2022-10-21, release date: 2023-11-01, Last modification date: 2024-11-06)

• Primary citation: Stein, C.S.,Hansen, G.,Ssebyatika, G.L.,Stroeh, L.,Benecke, T.,Menz, S.,Waldmann, J.-Y.,Vollmer, B.,Tipp, S.,Ochulor, O.,Herold, E.,Schwarzloh, B.,Mutschall, D.,Zischke, J.-Y.,Cordes, A.,Puppe, W.,Schneider, T.,Hinrichs, I.,Blasczyk, R.,Kleine-Weber, H.,Hoffmann, M.,Hoeper, M.,Kaiser, F.K.,Gonzalez-Hernandez, M.,Armando, F.K.,Ciurkiewicz, M.,Beythien, G.,Poehlmann, S.,Baumgaertner, W.,Gruenewald, K.,Osterhaus, A.,Schulz, T.,Krey, T.; Activity of broadly neutralizing antibodies against sarbecoviruses: a trade-off between SARS-CoV-2 variants and distant coronaviruses?; To be published,

Experimental method

X-RAY DIFFRACTION (1.7 Å)