8BE5
Crystal structure of SOS1-KRasG12V-Nanobody22-Nanobody75
This is a non-PDB format compatible entry.
Summary for 8BE5
Entry DOI | 10.2210/pdb8be5/pdb |
Descriptor | Son of sevenless homolog 1, Nanobody75, Isoform 2B of GTPase KRas, ... (5 entities in total) |
Functional Keywords | complex, stabilizer, signaling protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 4 |
Total formula weight | 109574.81 |
Authors | |
Primary citation | Fischer, B.,Wohlkonig, A.,Steyaert, J. ChILL & DisCO to discover Nanobodies that modulate protein-protein interactions and tune the SOS-Ras nucleotide exchange rate To Be Published, |
Experimental method | X-RAY DIFFRACTION (3.13 Å) |
Structure validation
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