8BE4

Crystal structure of SOS1-KRasG12V-Nanobody14

This is a non-PDB format compatible entry.

Summary for 8BE4

• Entry DOI: 10.2210/pdb8be4/pdb
• Descriptor: Son of sevenless homolog 1, Isoform 2B of GTPase KRas, Nanobody14, ... (4 entities in total)
• Functional Keywords: complex, stabilizer, signaling protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 95094.73

Authors

Fischer, B.,Wohlkonig, A.,Steyaert, J. (deposition date: 2022-10-21, release date: 2023-11-01)

• Primary citation: Fischer, B.,Wohlkonig, A.,Steyaert, J.; ChILL & DisCO to discover Nanobodies that modulate protein-protein interactions and tune the SOS-Ras nucleotide exchange rate; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.9 Å)