8B7D
Luminal domain of TMEM106B
Summary for 8B7D
Entry DOI | 10.2210/pdb8b7d/pdb |
Descriptor | Transmembrane protein 106B, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total) |
Functional Keywords | luminal domain, fibronectin type iii (fn3), 7-bladed beta-sandwich fold, receptor binding, sars cov2, covid19, membrane protein |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 23657.52 |
Authors | Pye, V.E.,Roustan, C.,Cherepanov, P. (deposition date: 2022-09-29, release date: 2023-07-19, Last modification date: 2024-05-01) |
Primary citation | Baggen, J.,Jacquemyn, M.,Persoons, L.,Vanstreels, E.,Pye, V.E.,Wrobel, A.G.,Calvaresi, V.,Martin, S.R.,Roustan, C.,Cronin, N.B.,Reading, E.,Thibaut, H.J.,Vercruysse, T.,Maes, P.,De Smet, F.,Yee, A.,Nivitchanyong, T.,Roell, M.,Franco-Hernandez, N.,Rhinn, H.,Mamchak, A.A.,Ah Young-Chapon, M.,Brown, E.,Cherepanov, P.,Daelemans, D. TMEM106B is a receptor mediating ACE2-independent SARS-CoV-2 cell entry. Cell, 186:3427-, 2023 Cited by PubMed: 37421949DOI: 10.1016/j.cell.2023.06.005 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.59 Å) |
Structure validation
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