8B7D

Luminal domain of TMEM106B

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Transmembrane protein 106B	polymer	199	22772.7	1	UniProt (Q9NUM4) Pfam (PF07092)	Homo sapiens (human)
2	B, C, D, E (A)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	4	Chemie (NAG)
3	F (A)	water	water		18.0	5	Chemie (HOH)

Sequence modifications

A: 118 - 274 (UniProt: Q9NUM4)

PDB	External Database	Details
Met 94	-	initiating methionine
Glu 95	-	expression tag
Thr 96	-	expression tag
Asp 97	-	expression tag
Thr 98	-	expression tag
Leu 99	-	expression tag
Leu 100	-	expression tag
Leu 101	-	expression tag
Trp 102	-	expression tag
Val 103	-	expression tag
Leu 104	-	expression tag
Leu 105	-	expression tag
Leu 106	-	expression tag
Trp 107	-	expression tag
Val 108	-	expression tag
Pro 109	-	expression tag
Gly 110	-	expression tag
Ser 111	-	expression tag
Thr 112	-	expression tag
Gly 113	-	expression tag
Asp 114	-	expression tag
Ala 115	-	expression tag
Ala 116	-	expression tag
Gln 117	-	expression tag
Gly 275	-	expression tag
Ser 276	-	expression tag
Gly 277	-	expression tag
Glu 278	-	expression tag
Asn 279	-	expression tag
Leu 280	-	expression tag
Tyr 281	-	expression tag
Phe 282	-	expression tag
Gln 283	-	expression tag
Ser 284	-	expression tag
Ala 285	-	expression tag
Gly 286	-	expression tag
His 287	-	expression tag
His 288	-	expression tag
His 289	-	expression tag
His 290	-	expression tag
His 291	-	expression tag
His 292	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	22772.7
Non-Polymers*	Number of molecules	4
	Total formula weight	884.8
All*	Total formula weight	23657.5

*Water molecules are not included.