8AE9

Human Aldose Reductase in Complex with a Hydroxyphenyl-Thiophen-Acid Inhibitor (Schl32357)

Summary for 8AE9

• Entry DOI: 10.2210/pdb8ae9/pdb
• Descriptor: Aldose reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 5-(5-(3-hydroxyphenyl)thiophen-2-yl)pentanoic acid, ... (5 entities in total)
• Functional Keywords: human aldose reductase, har, aldo-keto-reductase, schl32357 ligand, nadp+, diabetes, oxidoreductase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 36996.23

Authors

Hubert, L.-S.,Heine, A.,Klebe, G.,Reul, S. (deposition date: 2022-07-12, release date: 2023-08-16)

• Primary citation: Hubert, L.-S.,Heine, A.,Klebe, G.,Reul, S.; Human Aldose Reductase in Complex with a Hydroxyphenyl-Thiophen-Acid Inhibitor (Schl32357); To Be Published,

Experimental method

X-RAY DIFFRACTION (0.95 Å)