7ZLY

Crystal structure of human GPCR Niacin receptor (HCA2) expressed from Spodoptera frugiperda

7ZLY の概要

• エントリーDOI: 10.2210/pdb7zly/pdb
• 分子名称: Hydroxycarboxylic acid receptor 2,Soluble cytochrome b562, OLEIC ACID, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate (3 entities in total)
• 機能のキーワード: niacin receptor, hydroxycarboxylic acid receptor 2, hca2, gpcr, membrane protein structure, membrane protein
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 51868.83

構造登録者

Yang, Y.,Kang, H.J.,Gao, R.G.,Wang, J.J.,FiBerto, J.F.,Wu, L.J.,Tong, J.H.,Han, G.W.,Qu, L.,Wu, Y.R.,Pileski, R.,Li, X.M.,Zhang, X.C.,Zhao, S.W.,Kenakin, T.,Wang, Q.,Stevens, R.C.,Peng, W.,Roth, B.L.,Rao, Z.H.,Liu, Z.J. (登録日: 2022-04-17, 公開日: 2023-04-12, 最終更新日: 2024-02-07)

• 主引用文献: Yang, Y.,Kang, H.J.,Gao, R.,Wang, J.,Han, G.W.,DiBerto, J.F.,Wu, L.,Tong, J.,Qu, L.,Wu, Y.,Pileski, R.,Li, X.,Zhang, X.C.,Zhao, S.,Kenakin, T.,Wang, Q.,Stevens, R.C.,Peng, W.,Roth, B.L.,Rao, Z.,Liu, Z.J.; Structural insights into the human niacin receptor HCA2-G i signalling complex.; Nat Commun, 14:1692-1692, 2023; PubMed: 36973264; DOI: 10.1038/s41467-023-37177-6

実験手法

X-RAY DIFFRACTION (2.7 Å)