7ZF8

SARS-CoV-2 Omicron BA.2 RBD in complex with COVOX-150 Fab

Summary for 7ZF8

• Entry DOI: 10.2210/pdb7zf8/pdb
• Related: 7ZF3 7ZF4 7ZF5 7ZF6
• Descriptor: COVOX-150 heavy chain, COVOX-150 light chain, Spike protein S1 (3 entities in total)
• Functional Keywords: sars-cov-2, omicron, ba.1, ba.2, rbd, antibody, fab, covox-150, viral protein/immune system, viral protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 69901.36

Authors

Zhou, D.,Huo, J.,Ren, J.,Stuart, D.I. (deposition date: 2022-04-01, release date: 2022-06-01, Last modification date: 2024-01-31)

• Primary citation: Nutalai, R.,Zhou, D.,Tuekprakhon, A.,Ginn, H.M.,Supasa, P.,Liu, C.,Huo, J.,Mentzer, A.J.,Duyvesteyn, H.M.E.,Dijokaite-Guraliuc, A.,Skelly, D.,Ritter, T.G.,Amini, A.,Bibi, S.,Adele, S.,Johnson, S.A.,Constantinides, B.,Webster, H.,Temperton, N.,Klenerman, P.,Barnes, E.,Dunachie, S.J.,Crook, D.,Pollard, A.J.,Lambe, T.,Goulder, P.,Paterson, N.G.,Williams, M.A.,Hall, D.R.,Mongkolsapaya, J.,Fry, E.E.,Dejnirattisai, W.,Ren, J.,Stuart, D.I.,Screaton, G.R.; Potent cross-reactive antibodies following Omicron breakthrough in vaccinees.; Cell, 185:2116-2131.e18, 2022; PubMed: 35662412; DOI: 10.1016/j.cell.2022.05.014

Experimental method

X-RAY DIFFRACTION (2.95 Å)