7ZF4

SARS-CoV-2 Omicron RBD in complex with Omi-9 Fab and nanobody F2

Summary for 7ZF4

• Entry DOI: 10.2210/pdb7zf4/pdb
• Descriptor: Nanobody F2, Omi-9 heavy chain, Omi-9 light chain, ... (4 entities in total)
• Functional Keywords: sars-cov-2, omicron, rbd, antibody, fab, omi-3, ey6a, viral protein/immune system, viral protein
• Biological source: Lama glama (llama); More
• Total number of polymer chains: 4
• Total formula weight: 85447.32

Authors

Zhou, D.,Huo, J.,Ren, J.,Stuart, D.I. (deposition date: 2022-04-01, release date: 2022-06-08, Last modification date: 2024-01-31)

• Primary citation: Nutalai, R.,Zhou, D.,Tuekprakhon, A.,Ginn, H.M.,Supasa, P.,Liu, C.,Huo, J.,Mentzer, A.J.,Duyvesteyn, H.M.E.,Dijokaite-Guraliuc, A.,Skelly, D.,Ritter, T.G.,Amini, A.,Bibi, S.,Adele, S.,Johnson, S.A.,Constantinides, B.,Webster, H.,Temperton, N.,Klenerman, P.,Barnes, E.,Dunachie, S.J.,Crook, D.,Pollard, A.J.,Lambe, T.,Goulder, P.,Paterson, N.G.,Williams, M.A.,Hall, D.R.,Mongkolsapaya, J.,Fry, E.E.,Dejnirattisai, W.,Ren, J.,Stuart, D.I.,Screaton, G.R.; Potent cross-reactive antibodies following Omicron breakthrough in vaccinees.; Cell, 185:2116-2131.e18, 2022; PubMed: 35662412; DOI: 10.1016/j.cell.2022.05.014

Experimental method

X-RAY DIFFRACTION (4.18 Å)