7ZEZ

Trimolecular complex Cyp33-RRMdelta alpha : MLL1-PHD3 : H3K4me3

Summary for 7ZEZ

• Entry DOI: 10.2210/pdb7zez/pdb
• Related: 7ZEV 7ZEW 7ZEX 7ZEY
• NMR Information: BMRB: 34728
• Descriptor: Isoform 3 of Peptidyl-prolyl cis-trans isomerase E, MLL cleavage product N320, Histone H3, ... (4 entities in total)
• Functional Keywords: rrm, rna binding protein-structural protein complex, histone 3, h3k4me3, epigenetic, mll1 transcription regulation, infant leukemia, transcription
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 19325.52

Authors

Blatter, M.,Allain, F.,Meylan, C. (deposition date: 2022-03-31, release date: 2022-04-13, Last modification date: 2023-05-03)

• Primary citation: Blatter, M.,Meylan, C.,Clery, A.,Giambruno, R.,Nikolaev, Y.,Heidecker, M.,Solanki, J.A.,Diaz, M.O.,Gabellini, D.,Allain, F.H.; RNA binding induces an allosteric switch in Cyp33 to repress MLL1-mediated transcription.; Sci Adv, 9:eadf5330-eadf5330, 2023; PubMed: 37075125; DOI: 10.1126/sciadv.adf5330

Experimental method

SOLUTION NMR