7ZEZ

Trimolecular complex Cyp33-RRMdelta alpha : MLL1-PHD3 : H3K4me3

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003676	molecular_function	nucleic acid binding
A	0003723	molecular_function	RNA binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN B 1701

Chain	Residue
B	CYS1569
B	CYS1572
B	HIS1596
B	CYS1599

---

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN B 1702

Chain	Residue
B	CYS1588
B	CYS1591
B	CYS1621
B	CYS1624

---

Functional Information from PROSITE/UniProt

site_id	PS01359
Number of Residues	56
Details	ZF_PHD_1 Zinc finger PHD-type signature. CplCdkcyddddyeskm................................MqCgk..Cdrw.VHskCenlsdemyeilsnlpesva..........................YtCvnC

Chain	Residue	Details
B	CYS1569-CYS1624

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	78
Details	Domain: {"description":"RRM","evidences":[{"source":"PROSITE-ProRule","id":"PRU00176","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	61
Details	Zinc finger: {"description":"PHD-type 3","evidences":[{"source":"PROSITE-ProRule","id":"PRU00146","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	16
Details	Region: {"description":"Interaction with histone H3K4me3","evidences":[{"source":"PubMed","id":"20677832","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	Modified residue: {"description":"5-glutamyl serotonin; alternate","evidences":[{"source":"UniProtKB","id":"P68431","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine; by PKC","evidences":[{"source":"UniProtKB","id":"P68431","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	1
Details	Modified residue: {"description":"Symmetric dimethylarginine; by PRMT5; alternate","evidences":[{"source":"UniProtKB","id":"P68433","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	1
Details	Modified residue: {"description":"N6-methyllysine; alternate","evidences":[{"source":"UniProtKB","id":"P68432","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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