7ZDD
Crystal structure of TRIM33 PHD-Bromodomain isoform B in complex with H3K10ac histone peptide.
Summary for 7ZDD
Entry DOI | 10.2210/pdb7zdd/pdb |
Related | 5MR8 |
Descriptor | E3 ubiquitin-protein ligase TRIM33, Histone H3.X, 1,2-ETHANEDIOL, ... (5 entities in total) |
Functional Keywords | e3 ubiquitin-protein ligase, acetylation, transcription |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 23828.29 |
Authors | Caria, S.,Duclos, S.,Crespillo, S.,Errey, J.,Barker, J.J. (deposition date: 2022-03-29, release date: 2022-06-29, Last modification date: 2024-01-31) |
Primary citation | Sekirnik, A.R.,Reynolds, J.K.,See, L.,Bluck, J.P.,Scorah, A.R.,Tallant, C.,Lee, B.,Leszczynska, K.B.,Grimley, R.L.,Storer, R.I.,Malattia, M.,Crespillo, S.,Caria, S.,Duclos, S.,Hammond, E.M.,Knapp, S.,Morris, G.M.,Duarte, F.,Biggin, P.C.,Conway, S.J. Identification of Histone Peptide Binding Specificity and Small-Molecule Ligands for the TRIM33 alpha and TRIM33 beta Bromodomains. Acs Chem.Biol., 17:2753-2768, 2022 Cited by PubMed: 36098557DOI: 10.1021/acschembio.2c00266 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.625 Å) |
Structure validation
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