7Z63
Structure of the LecA lectin from Pseudomonas aeruginosa in complex with a biaryl-thiogalactoside
This is a non-PDB format compatible entry.
Summary for 7Z63
Entry DOI | 10.2210/pdb7z63/pdb |
Descriptor | PA-I galactophilic lectin, CALCIUM ION, [3-[(2~{S},3~{R},4~{S},5~{R},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]sulfanyl-4-methoxy-phenyl]-(3,4,5-trimethoxyphenyl)methanone, ... (5 entities in total) |
Functional Keywords | lectin, antiadhesive, thiogalactoside, rna binding protein, sugar binding protein |
Biological source | Pseudomonas aeruginosa PAO1 |
Total number of polymer chains | 4 |
Total formula weight | 53289.04 |
Authors | Varrot, A. (deposition date: 2022-03-10, release date: 2023-01-18, Last modification date: 2024-01-31) |
Primary citation | Bruneau, A.,Gillon, E.,Furiga, A.,Brachet, E.,Alami, M.,Roques, C.,Varrot, A.,Imberty, A.,Messaoudi, S. Discovery of potent 1,1-diarylthiogalactoside glycomimetic inhibitors of Pseudomonas aeruginosa LecA with antibiofilm properties. Eur.J.Med.Chem., 247:115025-115025, 2022 Cited by PubMed: 36549118DOI: 10.1016/j.ejmech.2022.115025 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.75 Å) |
Structure validation
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