7Z5S

Crystal Structure of botulinum neurotoxin A2 cell binding domain in complex with GD1a

This is a non-PDB format compatible entry.

Summary for 7Z5S

• Entry DOI: 10.2210/pdb7z5s/pdb
• Descriptor: Botulinum neurotoxin, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose-(1-4)-[N-acetyl-alpha-neuraminic acid-(2-3)]beta-D-galactopyranose, HEXAETHYLENE GLYCOL, ... (5 entities in total)
• Functional Keywords: ganglioside, neurotoxin, botulinum, receptor, gd1a, toxin
• Biological source: Clostridium botulinum
• Total number of polymer chains: 2
• Total formula weight: 102587.26

Authors

Gregory, K.S.,Acharya, K.R.,Liu, S.M.,Mahadeva, T.B. (deposition date: 2022-03-10, release date: 2022-06-08, Last modification date: 2024-01-31)

• Primary citation: Gregory, K.S.,Mahadeva, T.B.,Liu, S.M.,Acharya, K.R.; Structural Features of Clostridium botulinum Neurotoxin Subtype A2 Cell Binding Domain.; Toxins, 14:-, 2022; PubMed: 35622602; DOI: 10.3390/toxins14050356

Experimental method

X-RAY DIFFRACTION (2.1 Å)