7Z5S
Crystal Structure of botulinum neurotoxin A2 cell binding domain in complex with GD1a
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (AAA, BBB) | Botulinum neurotoxin | polymer | 433 | 50416.3 | 2 | UniProt (K4GGE0) Pfam (PF07953) Pfam (PF07951) | Clostridium botulinum | |
| 2 | C (DDD) | N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose-(1-4)-[N-acetyl-alpha-neuraminic acid-(2-3)]beta-D-galactopyranose | branched | 1128.0 | 1 | In PDB GlyTouCan (G78641QJ) | |||
| 3 | D, F (AAA, BBB) | HEXAETHYLENE GLYCOL | non-polymer | 282.3 | 2 | Chemie (P6G) | |||
| 4 | E (AAA) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 5 | G, H (AAA, BBB) | water | water | 18.0 | 291 | Chemie (HOH) |
Sequence modifications
AAA, BBB: 871 - 1296 (UniProt: K4GGE0)
| PDB | External Database | Details |
|---|---|---|
| Met 864 | - | initiating methionine |
| His 865 | - | expression tag |
| His 866 | - | expression tag |
| His 867 | - | expression tag |
| His 868 | - | expression tag |
| His 869 | - | expression tag |
| His 870 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 100832.5 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 1128.0 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 626.7 | |
| All* | Total formula weight | 102587.3 |
