7Z14

Cryo-EM structure of Torpedo nicotinic acetylcholine receptor in complex with a short-chain neurotoxin.

Summary for 7Z14

Entry DOI	10.2210/pdb7z14/pdb
EMDB information	14440
Descriptor	Acetylcholine receptor subunit alpha, Acetylcholine receptor subunit beta, Acetylcholine receptor subunit delta, ... (9 entities in total)
Functional Keywords	ion channel, toxin, membrane protein
Biological source	synthetic construct More
Total number of polymer chains	7
Total formula weight	286868.07
Authors	Nys, M.A.E.M.,Zarkadas, E.,Ulens, C.,Nury, H. (deposition date: 2022-02-24, release date: 2022-08-17, Last modification date: 2022-08-24)
Primary citation	Nys, M.,Zarkadas, E.,Brams, M.,Mehregan, A.,Kambara, K.,Kool, J.,Casewell, N.R.,Bertrand, D.,Baenziger, J.E.,Nury, H.,Ulens, C. The molecular mechanism of snake short-chain alpha-neurotoxin binding to muscle-type nicotinic acetylcholine receptors. Nat Commun, 13:4543-4543, 2022 Cited by PubMed: 35927270 DOI: 10.1038/s41467-022-32174-7 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.15 Å)

Structure validation