7Z14
Cryo-EM structure of Torpedo nicotinic acetylcholine receptor in complex with a short-chain neurotoxin.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D | Acetylcholine receptor subunit alpha | polymer | 437 | 50168.2 | 2 | UniProt (P02710) Pfam (PF02931) Pfam (PF02932) In PDB | Tetronarce californica (Pacific electric ray) | |
| 2 | B | Acetylcholine receptor subunit beta | polymer | 469 | 53731.8 | 1 | UniProt (P02712) Pfam (PF02931) Pfam (PF02932) In PDB | Tetronarce californica (Pacific electric ray) | |
| 3 | C | Acetylcholine receptor subunit delta | polymer | 501 | 57625.7 | 1 | UniProt (P02718) Pfam (PF02931) Pfam (PF02932) In PDB | Tetronarce californica (Pacific electric ray) | |
| 4 | E | Acetylcholine receptor subunit gamma | polymer | 489 | 56335.7 | 1 | UniProt (P02714) Pfam (PF02931) Pfam (PF02932) In PDB | Tetronarce californica (Pacific electric ray) | |
| 5 | F, G | Consensus short-chain short-chain alpha-neurotoxin ScNtx | polymer | 60 | 6849.0 | 2 | synthetic construct | ||
| 6 | H, K | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1559.4 | 2 | In PDB GlyTouCan (G83161QT) | |||
| 7 | I, J | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
| 8 | L | alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 951.9 | 1 | In PDB GlyTouCan (G08466KH) | |||
| 9 | C | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 7 |
| Total formula weight | 281727.4 | |
| Branched | Number of molecules | 5 |
| Total formula weight | 4919.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 221.2 | |
| All* | Total formula weight | 286868.1 |
