7YSF
Crystal structure of ZNF524 ZF1-4 in complex with telomeric DNA
Summary for 7YSF
Entry DOI | 10.2210/pdb7ysf/pdb |
Descriptor | Zinc finger protein 524, DNA (5'-D(*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*TP*AP*AP*CP*CP*CP*TP*AP*AP*CP*CP*C)-3'), ... (6 entities in total) |
Functional Keywords | c2h2 zinc finger, dna binding protein, transferase-dna complex, transferase/dna |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 3 |
Total formula weight | 25163.91 |
Authors | |
Primary citation | Braun, H.,Xu, Z.,Chang, F.,Viceconte, N.,Rane, G.,Levin, M.,Lototska, L.,Roth, F.,Hillairet, A.,Fradera-Sola, A.,Khanchandani, V.,Sin, Z.W.,Yong, W.K.,Dreesen, O.,Yang, Y.,Shi, Y.,Li, F.,Butter, F.,Kappei, D. ZNF524 directly interacts with telomeric DNA and supports telomere integrity. Nat Commun, 14:8252-8252, 2023 Cited by PubMed: 38086788DOI: 10.1038/s41467-023-43397-7 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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