7XVY
Human Estrogen Receptor beta Ligand-binding Domain in Complex with S-DPN
Summary for 7XVY
Entry DOI | 10.2210/pdb7xvy/pdb |
Descriptor | Estrogen receptor beta, Nuclear receptor coactivator 1, (2~{S})-2,3-bis(4-hydroxyphenyl)propanenitrile, ... (4 entities in total) |
Functional Keywords | inhibitor, transcription, transcription-inhibitor complex, transcription/inhibitor |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 4 |
Total formula weight | 58656.88 |
Authors | Furuya, N.,Handa, C. (deposition date: 2022-05-25, release date: 2022-07-20, Last modification date: 2023-11-29) |
Primary citation | Handa, C.,Yamazaki, Y.,Yonekubo, S.,Furuya, N.,Momose, T.,Ozawa, T.,Furuishi, T.,Fukuzawa, K.,Yonemochi, E. Evaluating the correlation of binding affinities between isothermal titration calorimetry and fragment molecular orbital method of estrogen receptor beta with diarylpropionitrile (DPN) or DPN derivatives. J.Steroid Biochem.Mol.Biol., 222:106152-106152, 2022 Cited by PubMed: 35810932DOI: 10.1016/j.jsbmb.2022.106152 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.544 Å) |
Structure validation
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