7X3P

Crystal structure of human SIRT5 in complex with diazirine inhibitor 9

7X3P の概要

• エントリーDOI: 10.2210/pdb7x3p/pdb
• 分子名称: NAD-dependent protein deacylase sirtuin-5, mitochondrial, 5-[[(5~{S})-6-[[(1~{S})-1-(4-hydroxyphenyl)-2-oxidanylidene-2-(prop-2-ynylamino)ethyl]amino]-6-oxidanylidene-5-[[4-[3-(trifluoromethyl)-1,2-diazirin-3-yl]phenyl]carbonylamino]hexyl]amino]-5-sulfanylidene-pentanoic acid, DI(HYDROXYETHYL)ETHER, ... (5 entities in total)
• 機能のキーワード: inhibitor, complex, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 31029.54

構造登録者

Li, G.-B.,Deng, J. (登録日: 2022-03-01, 公開日: 2023-09-06, 最終更新日: 2026-03-04)

• 主引用文献: Li, G.-B.,Deng, J.; Crystal structure of human SIRT5 in complex with diazirine inhibitor 9; To Be Published,

実験手法

X-RAY DIFFRACTION (1.56 Å)