7WNM

Structure of SARS-CoV-2 Gamma variant receptor-binding domain complexed with high affinity human ACE2 mutant (T27F,R273Q)

7WNM の概要

• エントリーDOI: 10.2210/pdb7wnm/pdb
• 分子名称: Angiotensin-converting enzyme 2, Spike protein S1, ZINC ION, ... (5 entities in total)
• 機能のキーワード: complex, viral protein
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 113353.43

構造登録者

Ma, R.Y.,Han, P.C.,Wang, Q.H.,Han, P. (登録日: 2022-01-18, 公開日: 2022-12-21, 最終更新日: 2024-11-20)

• 主引用文献: Zheng, A.,Wu, L.,Ma, R.,Han, P.,Huang, B.,Qiao, C.,Wang, Q.,Tan, W.,Gao, G.F.,Han, P.; A binding-enhanced but enzymatic activity-eliminated human ACE2 efficiently neutralizes SARS-CoV-2 variants.; Signal Transduct Target Ther, 7:10-10, 2022; PubMed: 35013100; DOI: 10.1038/s41392-021-00821-y

実験手法

X-RAY DIFFRACTION (2.7 Å)