7WLJ
CryoEM structure of human low-voltage activated T-type calcium channel Cav3.3 in complex with mibefradil (MIB)
Summary for 7WLJ
Entry DOI | 10.2210/pdb7wlj/pdb |
EMDB information | 32585 |
Descriptor | Voltage-dependent T-type calcium channel subunit alpha-1I, (1S,2S)-2-(2-{[3-(1H-benzimidazol-2-yl)propyl](methyl)amino}ethyl)-6-fluoro-1-(propan-2-yl)-1,2,3,4-tetrahydronaphthalen-2-yl methoxyacetate, 1,2-Distearoyl-sn-glycerophosphoethanolamine, ... (6 entities in total) |
Functional Keywords | mib, membrane protein |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 253011.83 |
Authors | |
Primary citation | He, L.,Yu, Z.,Geng, Z.,Huang, Z.,Zhang, C.,Dong, Y.,Gao, Y.,Wang, Y.,Chen, Q.,Sun, L.,Ma, X.,Huang, B.,Wang, X.,Zhao, Y. Structure, gating, and pharmacology of human Ca V 3.3 channel. Nat Commun, 13:2084-2084, 2022 Cited by PubMed: 35440630DOI: 10.1038/s41467-022-29728-0 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.9 Å) |
Structure validation
Download full validation report![Download](/newweb/media/icons/dl.png)
![Download](/newweb/media/icons/dl.png)