7WLJ
CryoEM structure of human low-voltage activated T-type calcium channel Cav3.3 in complex with mibefradil (MIB)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Voltage-dependent T-type calcium channel subunit alpha-1I | polymer | 2223 | 245373.0 | 1 | UniProt (Q9P0X4) Pfam (PF00520) Pfam (PF08016) | Homo sapiens (human) | Voltage-gated calcium channel subunit alpha Cav3.3,Ca(v)3.3 |
| 2 | B (A) | (1S,2S)-2-(2-{[3-(1H-benzimidazol-2-yl)propyl](methyl)amino}ethyl)-6-fluoro-1-(propan-2-yl)-1,2,3,4-tetrahydronaphthalen-2-yl methoxyacetate | non-polymer | 495.6 | 1 | Chemie (MWV) | |||
| 3 | C, D, F, G, H (A) | 1,2-Distearoyl-sn-glycerophosphoethanolamine | non-polymer | 748.1 | 5 | Chemie (3PE) | |||
| 4 | E (A) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 5 | I, J, L, N, O... (A) | CHOLESTEROL HEMISUCCINATE | non-polymer | 486.7 | 6 | Chemie (Y01) | |||
| 6 | K, M (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 245373.0 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 7638.8 | |
| All* | Total formula weight | 253011.8 |
