7WL6

Crystal structure of I73L mutated human transthyretin

Summary for 7WL6

Entry DOI	10.2210/pdb7wl6/pdb
Descriptor	Transthyretin, MAGNESIUM ION (3 entities in total)
Functional Keywords	ttr, transthyretin, human, transport protein
Biological source	Homo sapiens (human)
Total number of polymer chains	2
Total formula weight	29928.03
Authors	Nakagawa, M.,Obita, T.,Mizuguchi, M. (deposition date: 2022-01-12, release date: 2022-11-23, Last modification date: 2023-11-29)
Primary citation	Nakagawa, M.,Obita, T.,Mizuguchi, M. The hydrophobic residue Leu73 is crucial for the high stability and low aggregation properties of murine transthyretin. Biochem.J., 479:1999-2011, 2022 Cited by PubMed: 36098398 DOI: 10.1042/BCJ20220203 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.41800705321 Å)

Structure validation