7WIY
Cryo-EM structure of human TPH2 tetramer
Summary for 7WIY
Entry DOI | 10.2210/pdb7wiy/pdb |
EMDB information | 32540 |
Descriptor | Tryptophan 5-hydroxylase 2, FE (III) ION, IMIDAZOLE (3 entities in total) |
Functional Keywords | human, tryptophan 5-hydroxylase 2, tetramer, biosynthetic protein |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 4 |
Total formula weight | 225018.16 |
Authors | Zhu, K.F.,Liu, C.,Zhang, H.W.,Wang, D.P. (deposition date: 2022-01-05, release date: 2022-10-05, Last modification date: 2024-06-26) |
Primary citation | Zhu, K.,Liu, C.,Gao, Y.,Lu, J.,Wang, D.,Zhang, H. Cryo-EM Structure and Activator Screening of Human Tryptophan Hydroxylase 2. Front Pharmacol, 13:907437-907437, 2022 Cited by PubMed: 36046836DOI: 10.3389/fphar.2022.907437 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.09 Å) |
Structure validation
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