7WHR

Cryo-EM Structure of Leishmanial GDP-mannose pyrophosphorylase

Summary for 7WHR

• Entry DOI: 10.2210/pdb7whr/pdb
• EMDB information: 32509
• Descriptor: Nucleotidyl transferase family protein (1 entity in total)
• Functional Keywords: protozoan enzyme, leishmania donovani, sugar binding protein
• Biological source: Leishmania donovani
• Total number of polymer chains: 6
• Total formula weight: 250680.44

Authors

Xu, W.,Li, H.,Huang, C. (deposition date: 2021-12-31, release date: 2022-09-21, Last modification date: 2025-07-02)

• Primary citation: Li, H.,Ji, T.,Sun, Q.,Chen, Y.,Xu, W.,Huang, C.; Structural insights into selective inhibition of leishmanial GDP-mannose pyrophosphorylase.; Cell Discov, 8:83-83, 2022; PubMed: 36038534; DOI: 10.1038/s41421-022-00424-z

Experimental method

ELECTRON MICROSCOPY (3.4 Å)