7W7O
The crystal structure of human Calpain-1 protease core in complex with 14a
Summary for 7W7O
Entry DOI | 10.2210/pdb7w7o/pdb |
Descriptor | Calpain-1 catalytic subunit, N-[(2S)-3-(4-fluorophenyl)-1-oxidanylidene-1-[[(2S,3S)-3-oxidanyl-4-oxidanylidene-1-[(3S)-2-oxidanylidenepiperidin-3-yl]-4-[(phenylmethyl)amino]butan-2-yl]amino]propan-2-yl]-1-benzofuran-2-carboxamide, HYDROSULFURIC ACID, ... (5 entities in total) |
Functional Keywords | human protease, calpain-1, antiviral inhibitor, 14a, hydrolase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 38444.36 |
Authors | |
Primary citation | Zhao, Y.,Zhao, J.,Shao, M.,Yang, H.,Rao, Z. The crystal structure of human Calpain-1 protease core in complex with 14a To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.59 Å) |
Structure validation
Download full validation report