7VXY

Zika virus NS2B/NS3 protease bZipro(C143S) in complex with D-RKOR

Summary for 7VXY

Entry DOI	10.2210/pdb7vxy/pdb
Descriptor	Serine protease subunit NS2B, Serine protease NS3, Peptide inhibitor, ... (4 entities in total)
Functional Keywords	zikv, ns2b/ns3 protease, inhibitor, complex, viral protein
Biological source	Zika virus More
Total number of polymer chains	5
Total formula weight	52155.61
Authors	Xiong, Y.C.,Cheng, F.,Zhang, J.Y.,Su, H.X.,Hu, H.C.,Zou, Y.,Li, M.J.,Xu, Y.C. (deposition date: 2021-11-13, release date: 2022-09-14, Last modification date: 2023-11-29)
Primary citation	Xiong, Y.,Cheng, F.,Zhang, J.,Su, H.,Hu, H.,Zou, Y.,Li, M.,Xu, Y. Structure-based design of a novel inhibitor of the ZIKA virus NS2B/NS3 protease. Bioorg.Chem., 128:106109-106109, 2022 Cited by PubMed: 36049322 DOI: 10.1016/j.bioorg.2022.106109 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.901 Å)

Structure validation