7VXY
Zika virus NS2B/NS3 protease bZipro(C143S) in complex with D-RKOR
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C | Serine protease subunit NS2B | polymer | 53 | 5865.4 | 2 | UniProt (H8XX12) Pfam (PF01002) UniProt (by SIFTS) (Q32ZE1) In PDB | Zika virus | |
2 | B, D | Serine protease NS3 | polymer | 184 | 19924.6 | 2 | UniProt (H8XX12) Pfam (PF00949) UniProt (by SIFTS) (Q32ZE1) In PDB | Zika virus | |
3 | E | Peptide inhibitor | polymer | 4 | 575.7 | 1 | synthetic construct | ||
4 | water | water | 18.0 | 150 | Chemie (HOH) |
Sequence modifications
A, C: 2 - 53 (UniProt: H8XX12)
B, D: 1 - 177 (UniProt: H8XX12)
PDB | External Database | Details |
---|---|---|
Met 1 | - | initiating methionine |
PDB | External Database | Details |
---|---|---|
Met -6 | - | initiating methionine |
His -5 | - | expression tag |
His -4 | - | expression tag |
His -3 | - | expression tag |
His -2 | - | expression tag |
His -1 | - | expression tag |
His 0 | - | expression tag |
Ser 143 | Cys 1639 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 5 |
Total formula weight | 52155.6 | |
All* | Total formula weight | 52155.6 |