7VXX
Zika virus NS2B/NS3 protease bZipro(C143S) in complex with 4-amino benzamidine
Summary for 7VXX
Entry DOI | 10.2210/pdb7vxx/pdb |
Descriptor | Serine protease subunit NS2B, Serine protease NS3, P-AMINO BENZAMIDINE, ... (4 entities in total) |
Functional Keywords | zikv, ns2b/ns3 protease, inhibitor, complex, viral protein |
Biological source | Zika virus More |
Total number of polymer chains | 4 |
Total formula weight | 51716.06 |
Authors | Xiong, Y.C.,Cheng, F.,Zhang, J.Y.,Su, H.X.,Hu, H.C.,Zou, Y.,Li, M.J.,Xu, Y.C. (deposition date: 2021-11-13, release date: 2022-09-14, Last modification date: 2023-11-29) |
Primary citation | Xiong, Y.,Cheng, F.,Zhang, J.,Su, H.,Hu, H.,Zou, Y.,Li, M.,Xu, Y. Structure-based design of a novel inhibitor of the ZIKA virus NS2B/NS3 protease. Bioorg.Chem., 128:106109-106109, 2022 Cited by PubMed: 36049322DOI: 10.1016/j.bioorg.2022.106109 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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