7VPK

Cryo-EM structure of the human ATP13A2 (SPM-bound E2P state)

Summary for 7VPK

• Entry DOI: 10.2210/pdb7vpk/pdb
• EMDB information: 32068
• Descriptor: Polyamine-transporting ATPase 13A2, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, MAGNESIUM ION, ... (5 entities in total)
• Functional Keywords: atp13a2, park9, p-type atpase, membrane protein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 130030.44

Authors

Tomita, A.,Yamashita, K.,Nishizawa, T.,Nureki, O. (deposition date: 2021-10-17, release date: 2021-12-29)

• Primary citation: Tomita, A.,Daiho, T.,Kusakizako, T.,Yamashita, K.,Ogasawara, S.,Murata, T.,Nishizawa, T.,Nureki, O.; Cryo-EM reveals mechanistic insights into lipid-facilitated polyamine export by human ATP13A2.; Mol.Cell, 81:4799-4809.e5, 2021; PubMed: 34798056; DOI: 10.1016/j.molcel.2021.11.001

Experimental method

ELECTRON MICROSCOPY (3.5 Å)