7V9D

Plasmodium falciparum Prolyl-tRNA Synthetase (PfPRS) in Complex with inhibitor L95 and azetidine

Summary for 7V9D

• Entry DOI: 10.2210/pdb7v9d/pdb
• Descriptor: Proline--tRNA ligase, ~{N}-[4-[(3~{S})-3-cyano-3-cyclopropyl-2-oxidanylidene-pyrrolidin-1-yl]-6-methyl-pyridin-2-yl]-2-phenyl-ethanamide, (2S)-azetidine-2-carboxylic acid, ... (7 entities in total)
• Functional Keywords: protein translation, inhibitor, prs, atp pocket, double drug, ligase
• Biological source: Plasmodium falciparum
• Total number of polymer chains: 1
• Total formula weight: 58612.10

Authors

Manickam, Y.,Malhotra, N.,Sharma, A. (deposition date: 2021-08-24, release date: 2022-09-07, Last modification date: 2023-11-29)

• Primary citation: Manickam, Y.,Malhotra, N.,Sharma, A.; Plasmodium falciparum Prolyl-tRNA Synthetase (PfPRS) in Complex with inhibitor L95 and azetidine; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.937 Å)