7V9D
Plasmodium falciparum Prolyl-tRNA Synthetase (PfPRS) in Complex with inhibitor L95 and azetidine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Proline--tRNA ligase | polymer | 497 | 57801.2 | 1 | UniProt (Q8I5R7) Pfam (PF00587) Pfam (PF03129) Pfam (PF09180) In PDB | Plasmodium falciparum | Prolyl-tRNA synthetase,ProRS |
| 2 | A | ~{N}-[4-[(3~{S})-3-cyano-3-cyclopropyl-2-oxidanylidene-pyrrolidin-1-yl]-6-methyl-pyridin-2-yl]-2-phenyl-ethanamide | non-polymer | 374.4 | 1 | Chemie (JE6) | |||
| 3 | A | (2S)-azetidine-2-carboxylic acid | non-polymer | 101.1 | 1 | Chemie (02A) | |||
| 4 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
| 5 | A | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
| 6 | A | 1,4-BUTANEDIOL | non-polymer | 90.1 | 1 | Chemie (BU1) | |||
| 7 | water | water | 18.0 | 296 | Chemie (HOH) |
Sequence modifications
A: 254 - 746 (UniProt: Q8I5R7)
| PDB | External Database | Details |
|---|---|---|
| Gly 250 | - | expression tag |
| Ala 251 | - | expression tag |
| Met 252 | - | expression tag |
| Ala 253 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 57801.2 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 810.9 | |
| All* | Total formula weight | 58612.1 |
