7UWT
Structure of Oxygen-Insensitive NAD(P)H-dependent Nitroreductase NfsB_Vv F70A/F108Y (NTR 2.0) in complex with FMN at 1.85 Angstroms resolution
Summary for 7UWT
Entry DOI | 10.2210/pdb7uwt/pdb |
Descriptor | Dihydropteridine reductase, FLAVIN MONONUCLEOTIDE, ACETATE ION, ... (5 entities in total) |
Functional Keywords | nitroreductase, oxidoreductase, flavoenzyme, metronidazole reductase |
Biological source | Vibrio vulnificus |
Total number of polymer chains | 2 |
Total formula weight | 51317.88 |
Authors | Sharrock, A.V.,Arcus, V.,Mumm, J.S.,Ackerley, D.F. (deposition date: 2022-05-03, release date: 2022-05-18, Last modification date: 2023-10-25) |
Primary citation | Sharrock, A.V.,Mumm, J.S.,Bagdziunas, G.,Cenas, N.,Arcus, V.L.,Ackerley, D.F. The Crystal Structure of Engineered Nitroreductase NTR 2.0 and Impact of F70A and F108Y Substitutions on Substrate Specificity. Int J Mol Sci, 24:-, 2023 Cited by PubMed: 37047605DOI: 10.3390/ijms24076633 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.85 Å) |
Structure validation
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