7UWT
Structure of Oxygen-Insensitive NAD(P)H-dependent Nitroreductase NfsB_Vv F70A/F108Y (NTR 2.0) in complex with FMN at 1.85 Angstroms resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Dihydropteridine reductase | polymer | 217 | 24149.3 | 2 | UniProt (A0A347SKZ6) UniProt (by SIFTS) (Q7MCD2) | Vibrio vulnificus | Oxygen-insensitive NAD(P)H nitroreductase |
| 2 | C, E (A, B) | FLAVIN MONONUCLEOTIDE | non-polymer | 456.3 | 2 | Chemie (FMN) PubChem (710) PubChem (8965) PubChem (643976) PubChem (5702760) PubChem (7048779) PubChem (7048781) PubChem (23585816) PubChem (51435500) PubChem (51435503) PubChem (15559251) | |||
| 3 | D, F (A, B) | ACETATE ION | non-polymer | 59.0 | 2 | Chemie (ACT) PubChem (175) | |||
| 4 | G, H, I (B) | polyethylene glycol | non-polymer | 662.8 | 3 | Chemie (P4K) PubChem (76871872) | |||
| 5 | J, K (A, B) | water | water | 18.0 | 183 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 217 (UniProt: A0A347SKZ6)
| PDB | External Database | Details |
|---|---|---|
| Ala 70 | Phe 70 | engineered mutation |
| Tyr 108 | Phe 108 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 48298.7 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 3019.2 | |
| All* | Total formula weight | 51317.9 |
