7ULJ

Hsp90b N-terminal domain in complex with 42C

Summary for 7ULJ

Entry DOI	10.2210/pdb7ulj/pdb
Descriptor	Heat shock protein HSP 90-beta, N,N-dimethyl-7H-purin-6-amine, (4S)-2-METHYL-2,4-PENTANEDIOL, ... (5 entities in total)
Functional Keywords	hsp90 isoform, molecular chaperone, hsp90b, and ligand binding, chaperone
Biological source	Homo sapiens (human)
Total number of polymer chains	4
Total formula weight	100173.06
Authors	Stachowski, T.R.,Nithianantham, S.,Vanarotti, M.,Fischer, M. (deposition date: 2022-04-05, release date: 2023-04-12, Last modification date: 2023-10-25)
Primary citation	Stachowski, T.R.,Nithianantham, S.,Vanarotti, M.,Lopez, K.,Fischer, M. Pan-HSP90 ligand binding reveals isoform-specific differences in plasticity and water networks. Protein Sci., 32:e4629-e4629, 2023 Cited by PubMed: 36938943 DOI: 10.1002/pro.4629 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.82 Å)

Structure validation